Parent Page: Research Support id: 33827 Active Page: Clinical Research Data Warehouse (CRDW) id: 33150

Clinical Research Data Warehouse

The Clinical Research Data Warehouse (CDRW) is a partnership between OU College of Medicine, Oklahoma Shared Clinical and Translational Resources (OSCTR), OU Health, and the Oklahoma Health Care Authority/Meditech. The CDRW is working to connect electronic medical records (EMRs) to research and quality improvement/quality assurance (QI/QA) communities. The CDRW supports OUHSC's ability to compete for grants by allowing access to inpatient and outpatient EMRs. CDRW also helps improve care for patients by supporting the facilitation of meaningful local surveillance programs. CDRW is committed to avoiding undesirable work-arounds which create risk for duplicate data entry, poor data quality, and poorly managed smaller databases.

Some of the frequently requested services to CRDW include: 

  • Feasibility assessments in preparation for research
  • Static patient eligibility for research (patient pools)
  • Rolling patient eligibility
  • Clinical outcomes for retrospective investigations
  • Administrative outcomes for quality improvement
  • Program evaluation

Investigators who would like to request support from CDRW should submit a request form:

Request CRDW Support

Find us on GitHub!

CRDW workflow for researchers

After you submit a request (use the button link at the top of this webpage), you will be contacted by a member of the CRDW analytics team to set up a meeting to discuss your data needs. Please note, the CRDW provides support in access to data; however, we do not advise on statistical analysis plans or methodology. For support with methodology, please check out resources at BBMC and OSCTR

At this meeting, we will discuss your request and learn more about how we can address your study's needs. Topics of conversation will include:

  • Inclusion criteria and how this can be identified in EMR (e.g., ICD codes, CPT codes, visit locations, medication lists, etc.). 
    • If IRB is already approved, it can be helpful to have examples available to review so we can validate and verify we are identifying the correct data.
  • Timelines/deadlines
  • IRB considerations

For some projects, we may need to send your team files to specify some criteria. For instance, we may send you an ICD range or all medications that have a certain set of characters and request that you define which are the appropriate to use by choosing True/False for each type.  

The time it will take to process your request will vary widely depending on several factors including existing workloads, deadlines, how complicated a request is, how responsive your team is about questions, and needing to do additional processing to access data.  CRDW is obligated to prioritize projects that contribute funding to support our mission.

Once we have assembled your data, we will meet with you to verify we have correctly retrieved data that meets the needs and the IRB-approved specifications of your project.  

If your project will require use of a larger dataset, or if you are sharing any data outside of OUHSC/OU Health (even in aggregate), you must also submit a request to the Clinical Research Informatics Oversight Committee at .

About CRDW data ingestion process

As shown on the diagram below, the CDRW can be represented by six columns. 

The first column consist of EMR and other databases. To feed into the data warehouse, we receive nightly refreshes of data that are then cleaned and restructured using Extract, Transform, and Load (ETL) processes (second column) and stored in the data warehouse (third column). 

When an investigation receives IRB approval, we can develop a smaller database that contains the specific dataset needed for their analysis (4th and 5th columns). 

Finally, individual investigators and authorized personnel following all applicable rules and laws can access these data at any time.

CRDW Data Sources

  • Legacy EHR systems:
    • Centricity/Athena
    • Billing and Claims
    • Meditech
  • Epic 
  • Dozens of departmental sources
  • Biomedical Research Data
  • Provider data
  • External agencies (Oklahoma State Department of Health, Oklahoma Department of Human Services, etc.)
  • Administrative cost

National Registry Projects CRDW Supports

  • Oncology Research Information Exchange Network (ORIEN)
  • Oncologic Outcomes in Renal Cell Carcinoma
  • N3C (National COVID Cohort Collaborative)
    • Investigators who would like access to the N3C Enclave should reach out to us!

Example IRB Protocol Language for Projects using CRDW data

Data will be obtained from (*list data sources here*), (*some/all*) of which currently reside as data sources in the OUHSC Clinical Research Data Warehouse (CRDW). The CRDW is managed by the Biomedical and Behavioral Methodology Core (BBMC; Data from these systems will be queried to: (*modify as needed: identify eligible participants and extract clinical information to support recruitment and/or analysis*). 

Eligible participants will be meet the following conditions for inclusion: (*list age, gender, race, ethnicity, diagnosis, visit/admission, location of care, or other requirements*). Data extracted to support this study will include: (*select all that apply: patient identifiers, demographics, appointment/visit information, labs, medications, orders, provider notes*), and other relevant clinical documentation. Information will be released to authorized study personnel via (*select the preferred method of delivery: a csv file, REDcap, write to secure file server, other*).

CRDW Team Contact Info

  General Inquiries 
William Beasley, Ph.D. BBMC Director of Informatics
Ashley Thumann, MHA EHR Liaison, Senior Data Analyst
Arnold Kanagwa, MS Sr. Data Scientist
Geneva Marshall, MS, MHR      Sr. Data Scientist