https://research.ouhsc.edu/research-support Parent Page: Research Support id: 33436 Active Page: Research Clinical Informatics Resources id: 33827

Researcher Clinical Informatics Resources

The OUHSC Clinical Research Informatics team supports researchers in navigating and accessing the following resources and tools:

Clinical data extraction for Research

Clinical Research Data Warehouse

The OUHSC Clinical Research Data Warehouse contains data from multiple EHR and related data systems in support of clinical research. The CRDW team provides project-specific datasets to researchers based on project specifications (inclusion criteria, date ranges, etc.).

CRDW EHR data sources include:

  • Epic
  • Legacy Centricity/athenaFlow
  • Legacy Meditech
  • Legacy Billing and Claims

For a more detailed description of the process or to submit a request, please visit the CRDW webpage.

Epic Workbench Reports

Reporting Workbench is a tool within Epic allowing users to perform custom, real-time queries on patient data, and patients identified in these queries may be contacted (one at a time) via MyChart. Workbench Reports display basic patient contact information and links directly to charts so they may be quickly reviewed to manage tasks or further review the chart for eligibility and identify exclusion criteria. 

Epic SlicerDicer

SlicerDicer is an intuitive, robust point-and-click method of rapidly identifying patients meeting study criteria. Data can be viewed visually in graphic formats, and patient lists can be viewed directly for chart review and patient contact (if IRB is approved, and use of SlicerDicer/self-service EHR extraction is specified in the IRB application and protocol).  Using the SlicerDicer tool in Epic, users may select criteria (e.g., diagnoses, age ranges, lab results, etc.) and perform some basic analyses on the populations selected, such as counts, percentages, demographic breakdowns, etc. These analyses can be viewed in aggregate by any Epic user (cells < 10 are censored).  This can support Feasibility evaluation without exposing PHI.

We encourage researchers who plan to use SlicerDicer for research to attend training to obtain proficiency in using the tool. Please email EpicTraining@ouhealth.com to request training.  Additionally, we also encourage newer users of SlicerDicer to request an Epic Research Analyst to review your SlicerDicer report to ensure accuracy. For this support, please submit an OU Health IT ticket routed to Epic Research.

Epic Best Practice Advisories (BPAs)

BPAs are a decision support tool used to support better patient outcomes, and they can be tailored to a specific audience. When a patient meeting the BPA criteria presents for an encounter, the provider will be presented with a summary of the study and why the patient qualifies. If a provider indicates patient interest, this will send inbox alert to a research coordinator to let them know that the patient is eligible for the study and interested.  This is useful for identifying research subjects eligible for a study, and allowing a provider who already has a relationship with the patient to make the initial contact and request permission for a member of the study team to contact them about the study.

Users should submit a ServiceNow request routed to Epic Research. An Epic Research Analyst will contact you to discuss study requirements. Once the BPA is activated, providers/research coordinators will automatically be notified of eligible patients, and authorized individuals will be able to access reports of BPAs, similarly to Workbench Reports.

Access legacy EHR via ELLKAY data lake

Coming soon...

EMERSE (Electronic Medical Record Search Engine)

Coming soon to OUHSC...

Chart Abstraction Made Easy

EMERSE (Electronic Medical Record Search Engine) is software that helps researchers accurately find and extract important patient details like diagnoses, medications, procedures, and complications from clinical notes. EMERSE is easy for non-technical people to use and enables health research that was previously inefficient or nearly impossible. The functionality enables users to quickly and easily search notes in Epic (similar to a Google search) and retrieve data (terms are highlighted within the notes for rapid concept identification) that are not otherwise available in structured fields, such as ICD codes and lab values. EMERSE has the potential to save study personnel hours on chart review for data collection.

EMERSE cohorts can be created in Epic and exported to REDCap via the REDCap on FHIR interface. 

EMERSE use cases: 

  • Feasibility study/Preparatory to research – estimate counts of patients meeting eligibility criteria​
  • Rare diseases – quickly find mentions of rare diseases, especially helpful when diagnosis codes are too broad or used incorrectly. ​
  • Eligibility determination – Quickly evaluate complicated eligibility criteria to check free text documents for mentions of specific criteria​
  • Data abstraction – For research subjects, treatment courses, side effects, etc. can be abstracted with ease​
  • Quality improvement ​
  • Risk Management – rapidly identify patients with device/implant recalls​
  • Clinical chart review as a part of patient care (e.g., searching chart to locate a medication taken multiple years ago for a specific condition)​

For more details about EMERSE, please visit https://project-emerse.org/

For the EMERSE user guide, please visit https://project-emerse.org/documentation/user_guide.html

Analytics Resources and Collaboration

Epic Cosmos

Cosmos (https://cosmos.epic.com/) is a harmonized, groomed dataset including longitudinal records from over 1400 hospitals and 32.5K clinics with over 11 billion encounters for 242 million distinct patients including lab results, procedures, hospital visits, vitals, demographics, social determinants of health, and much more. Cosmos is accessible to all researchers affiliated with a Cosmos participating organization. Users who take a short series of courses are able to use the Epic SlicerDicer tool to identify and evaluate patterns, trends, counts, and various cross-sectionality views of existing data for all institutions that contribute data to Cosmos. Cosmos is used to answer research questions and to learn more about institutional quality control. Obtaining access to a new project in Cosmos is fast, and answers can be obtained on-demand.  Cosmos has an elected governance board, and all users must agree to the Cosmos Rules of the Road to uphold the standards of use.   

Researchers interested in obtaining access to Cosmos should contact bbmc@ouhsc.edu  

N3C

Read more about N3C

Researchers interested in accessing N3C should reach out to bbmc@ouhsc.edu

Study support and data management

REDCap

REDCap is a browser-based, metadata-driven electronic data capture software created by Vanderbilt University. The REDCap Consortium is composed of nearly 900 active institutional partners from more than 70 countries. Programming, networking or database experience is not needed to use REDCap. It is designed to use simple interfaces that handle these details automatically. REDCap is secure and web-based: you can input data or build an online survey or database from anywhere in the world over a secure web connection with authentication and data logging. REDCap allows multi-site access for research that uses multiples sites and institutions. 
 

OnCore

OnCore-ByAdvarra-FullColor

The Online Collaborative Research Environment (OnCore) is a comprehensive web-based clinical trial management system (CTMS). OnCore offers investigators and research coordinators a centralized application to manage the complete life cycle of a study, from start-up and pre-award activities to closure. Key features of OnCore include protocol management, subject management, financial management, biospecimen management, patient registries, safety monitoring, and reporting. 

Read more about OnCore

eREG

Advarra's eRegulatory Management System (eREG) is a 21 CFR Part 11 compliant system designed to adapt to and streamline research site regulatory workflows. Features available for use in eREG include routing an signing documents, delegation of authority, applying shared documents across multiple protcols, securely allowing access to sponsors and monitors, managing multi-site trials, and effectively acting as the research binder for study protocols. eREG is able to link with OnCore for protocol management. 

eREG is used campuswide for oncology research, and implementation is underway for non-oncology studies. Non-oncology study teams interested in learning more about using eReg for regulatory management, email CTMS-Support@ouhsc.edu, and we will work with you to assess your team's needs and facilitate system access. 

Regulatory support

CRIOC

The Clinical Research Informatics Oversight Committee (CRIOC) reviews requests for using patient health data for research and/or sharing patient health data with any external entity for research purposes. CRIOC is comprised of legal, compliance, privacy, security, and research officials from the OU Health and Health Sciences Center (HSC) administration. CRIOC weighs institutional liabilities and any risk to data impacted by the usage and exchanges of these data.

Read more about CRIOC

Study monitor data access requests