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OUHSC Research News – Monday, June 26, 2023


Published: Friday, June 23, 2023

Notices and Reminders

OCAST FY24 Applications: The only OCAST programs to have funding for award in FY2024 (July 1, 2023 – June 30, 2024) are the Oklahoma Applied Research Support (OARS) program and the Intern Partnership program.  The OCAST Health Research, Health Research Fellowship and Plant Science programs will go unfunded in FY2024.  Please note projects supporting industry in the three targeted strategic areas with the greatest probability of maximum return, Biotech/life sciences (including Ag-Tech), aerospace/autonomous systems and defense, and energy diversification are eligible for the OARS program.  The OARS program in FY2024 will not offer proof-of-concept funding. Applications are open August 2nd.

 

NIH Reminder: The Vertebrate Animals Section (VAS) of the NIH applications should be used to provide a concise description of the procedures on live vertebrate animals. However, per the NIH instructions, the justification for the number of animals, sex, ages, and other biological variables should be described in the Research Strategy. For more information on VAS requirements, including a checklist and detailed instructions, please refer to the Vertebrate Animals Section at the NIH Office for Laboratory Animal Welfare webpage here: https://olaw.nih.gov/guidance/vertebrate-animal-section.htm. 

 

Robert M. Bird Health Sciences Library is providing resources for researchers: 

  • HSTalks - The Biomedical & Life Sciences Collection - Animated, online, audio-visual lectures, seminar-style talks and case studies

Henry Stewart Talks Ltd (HSTalks) is a leading provider of specially prepared, animated, online, audio-visual lectures, seminar-style talks and case studies for medical schools, business schools, universities and commercial enterprises in over 60 countries around the world.  Unlimited access 24 hours a day every day of the year.

Editors and lecturers are leading world experts and practitioners, including Nobel Laureates, drawn from academia, research institutes, commerce, industry, the professions and government. The collections are continuously expanded and updated and may be easily embedded in online learning environments such as Moodle and Blackboard.

  • JoVE Video Library – Videos demonstrating laboratory Protocols

The complete JoVE video library provides the breadth and depth needed to meet the needs of science students and researchers at all levels.  With videos illustrating basic and advanced concepts and methods, novel experimental research and more, JoVE videos maximize productivity from the classroom to the advanced research laboratory.

  • Publication Support Libguide (library guide)

The Publication Support Libguide created by BHS Library faculty outlines publication support that is available through the library.  Topics include selecting a journal for publication, authorship, reporting guidelines, financial assistance, and more.  This and other guides can be found on the library homepage under Guides & Tutorials.

  • Northern Light Life Sciences Conference Abstracts

Northern Light’s conference abstracts and posters collection includes content from 1,600 life sciences industry conferences from 2010-present.  This is one of several databases the library purchases on behalf of OUHSC students, faculty, and staff that is available through the Ovid platform.  Over 150 databases and other collections are accessible from the library’s homepage.  On the home page navigate to More Resources using the menu on the left and click on All Databases & Resources A-Z to browse the list.

 

Nature Masterclasses- Professional Development Training for Researchers

Accessing the OUHSC Library Institutional Subscription

Nature Masterclasses provides professional development training for researchers — via online courses and on-demand workshops.  The BHS Library subscribes to an online subscription which is available 24/7, so it’s convenient for the researcher’s schedule.  Periodically, live webinars are offered free to subscribers.

From designing your experiments to advancing your career, Nature Masterclasses offer on-demand courses that cover the whole research cycle, so there is something for everyone, at whatever stage of your career. 

Content includes courses for research design, securing funding, experiment and analyse, write and publish, share and disseminate, develop your career, and work with others.

If you would like to access the OUHSC Nature Masterclasses online (NMO) subscription provided by the library, register using the instructions below.

  • Use this link or go to the library's home page and navigate to More Resources à All databases & Resources A-Z, Select the letter N and scroll down to Nature Masterclasses à Click on the link
  • You will need to register while on the campus network (or VPN) to create a login. Ignore language to request a quote or buy a subscription, and register using the button in the top right hand corner.
  • Once registered you can use your login from anywhere. 
  • NOTE:  While on the campus network (or VPN) you will have to login to NMC approximately every 6 months to verify that you are a valid user.  You must have valid OUHSC credentials to continue to use NMC.

 

Workshops and Seminars

Omics for the Biomedical researcher workshop

This fall we are planning on having a workshop where we will teach biomedical researchers how to perform basic informatics analysis, with a particular focus on single cell RNA sequencing. In this hands-on workshop, we will teach participants how run raw data (in the form of FASTQ files) through Cellranger, upload the data into R, process the data, and generate usable visualizations including UMAPs, Heatmaps, and volcano plots. We will also teach researchers how to perform ligand-receptor and pseudotime analysis.  These analyses will be done using bash, linux, R, and python platforms. This workshop will take place over the course of ~four months and will require the participant to attend one, four-hour session per week (12 sessions total). The course will be held in person at the Samis Center, East Boardroom. No fee will be charged for the workshop. A description of the requirements and applications materials is listed below. We anticipate accepting 10 applicants into the workshop. Applications are due by July 15th, 2023. Please send application materials to Kurt Zimmerman (kurt-zimmerman@ouhsc.edu).

Please see attached document for more complete information and the schedule of classes.

 

OUHSC Funding Opportunities

Presbyterian Health Foundation (PHF) Bridge Grant Program – Request For Applications

·         Cycle II PHF Bridge Grant Program Deadline: July 7, 2023

The primary objective of the PHF Bridge Grant Program is to provide funding to enhance OUHSC faculty competitiveness for extramural funding. OUHSC Principal Investigators are eligible if they  meet the following criteria: 1) have submitted an extramural application within the past 18 months that was scored but not funded, 2) are requesting over $750,000 in total direct costs and over  $200,000 in total facilities and administration (F&A) costs; and 3) received a review that ranks applications and provides critiques.

IMPORTANT UPDATE: This program can now provide funding for up to $100,000 for one year. SALARY and FRINGE BENEFITS may be requested for the Principal Investigator(s) up to $25,000 in total (salary + fringe benefits = $25,000) with the remaining portion, $75,000, used to support the project costs. Guidelines and Application Form are attached or can be found at https://research.ouhsc.edu/research-administration/grants/funding-opportunities/phf-funding. If you have any questions, please email  VPR@ouhsc.edu.

 

Office of Technology Commercialization presents the following opportunity for researchers to engage with industry (click here for more information, or email otc@ou.edu or gina-mcmillen@ouhsc.edu).  

  • A world leading crop science company seeks research related to methods of increasing fatty acid or oil production in annual crops.  Approaches of interest include native genes and pathways that can be changed via traditional breeding or gene editing and transgenes that can be introduced.  Out of scope are genes or pathways of animal origin and plant cultivation conditions (i.e. fertilisers) to increase oil accumulation and altering oil composition in non-terrestrial crops.    Submission entails a one-page 200-300 word non-confidential brief. (deadline 07/10).
  • Hoya Surgical Optics is seeking opportunities related to intraocular lens development, preloaded IOL injectors and biocompatibility of hydrophobic lens materials.  Approaches of interest include innovations in optical and mechanical lens design, modification of lens materials, novel injector materials and methods, solutions to lens epithelial cell adhesion, and novel optical equipment. Out of scope: research relating to contact lenses or scleral lenses.    Submission entails a one-page 200-300 word non-confidential brief. (deadline 08/01).
  • Biotype, an incubator initiative of VIP, is searching for agri-food biotech innovations ready for early stage spin-out support.  Areas of interest include plant biotechnology towards beneficial agronomic traits, novel active ingredients or sustainable products for crop protection, molecular farming for production of products such as supplements, and technologies to improve health and wellbeing of humans or animals.  Out of scope: opportunities related to IT or robotics and business to consumer products.  Submission entails a one-page 200-300 word non-confidential brief. (deadline 08/01).
  • Smart Immune, who has recently developed an innovative bioproduction method for cultivating T cell progenitors, is seeking a CAR construct that enables precise recognition of tumor antigens, in order to develop CAR-T cell therapy for treatment of hematological and/or solid tumor malignancies.  All types of CARs, CAR-T generation methods and mechanisms of action within oncology are of interest.  Out of scope: screening platforms for receptor discovery, CAR constructs designed to target antigens unrelated to oncology, novel CAR-T cell delivery methods/routes of administration. Submission entails a one-page 200-300 word non-confidential brief. (deadline 08/01).

 

NIH Notices 

NOTE: When only one application is allowed per Institution according to the sponsor instructions, a one-page letter of intent summarizing the proposed project should be submitted to the Vice President for Research at least two months prior to the application deadline (unless otherwise noted).  The letters of intent will be reviewed and a single application will be chosen for submission from the University.

 

NIH Funding Opportunities

 

Other Funding Opportunities

Susan G. Komen: Career Transition Awards (CTA)

Description: Through this NEW grant mechanism, we seek to support outstanding senior postdoctoral and clinical fellows working under the guidance of a mentor to launch their competitive, independent breast cancer research careers.  With these Career Transition Awards (CTA), Komen will continue to support the training and career development of the next generation of leaders, while promoting research that will help us achieve our strategic imperatives and end breast cancer.

The Career Transition Awards provide up to five years of funding in two phases: Phase 1 supports the final years of mentored, postdoctoral training and Phase 2 supports the independent research of the early career, tenure-track investigators. Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research goals and priorities and mission to save lives from breast cancer.

Letters of Intent Due: July 14, 2023, by 1 p.m. EST

Full Application Due: September 20, 2023, by 1 p.m. EST

Link to Full Announcement: https://www.komen.org/breast-cancer-research/grants/opportunities/

 

HRSA Behavioral Health Workforce Education and Training- Children, Adolescents, and Young Adults (BHWET-CAY) Program for Professionals

Description: The purpose of the BHWET-CAY Program is to increase the supply and distribution of behavioral health providers in rural and underserved communities to address the behavioral health needs of children, adolescents, and young adults (ages 16-25). The BHWET-CAY Program aims to address specific bottlenecks in recruiting and training behavioral health professionals including by providing stipends to support trainees during their clinical/experiential training and by increasing the supply of and training for clinical supervisors overseeing trainees. 

Application deadline: 7/14/2023

Link to Full Announcement: https://www.hrsa.gov/grants/find-funding/HRSA-23-131

 

HRSA Maternity Care Nursing Workforce Expansion (MatCare) Program

Description: The purpose of the MatCare Program is to support accredited nurse midwifery programs to train nurse midwives through trainee scholarships, stipends, curriculum enhancement, and community-based training. The program seeks to grow and diversify the maternal and perinatal health nursing workforce through support for education and training in rural and underserved communities. 

Application deadline: 7/14/2023

Link to Full Announcement: https://www.hrsa.gov/grants/find-funding/HRSA-23-120

 

Cystic Fibrosis (CF) Foundation: Newborn Screening Improvement Program Award

Description: Applications are now being accepted for the 2023 Screening Improvement Program (SIP) Award for Optimizing the Diagnosis of Infants. The application deadline is July 10, 2023. Please review the SIP Award Policies and Guidelines for full details on the award and instructions for the application process. For questions, contact Marissa Rollins (mrollins@cff.org).

 

HRSA Primary Care Training and Enhancement-Language and Disability Access (PCTE-LDA)

Description: The purpose of the PCTE-LDA program is to develop curricula and to train medical students, physician assistant students, and primary care medical residents to provide high quality primary care services to individuals with limited English proficiency (LEP) and/or individuals with physical disabilities and/or intellectual and developmental disabilities (IDD) with goals of improving health outcomes for these populations. 

Application deadline: 7/3/2023

Link to Full Announcement: https://www.hrsa.gov/grants/find-funding/HRSA-23-123

 

ICRG: Grant Support for Research on Online Gambling and Potential Harms

Description: The International Center for Responsible Gaming (ICRG) invites investigators to apply for a grant to study online gambling, and potential health harms, in the US.

Applicants may request up to a total of $75,000 per year for up to two years plus 15 percent in Facilities & Administration costs. The ICRG will support one grant award under this initiative, which was made possible by support from the Boyd Gaming Corporation.

Application deadline: 9/29/2023

Link to Full Announcement: https://www.icrg.org/information/apply-for-icrg-funding

 

BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)

Description: Invasive surgical procedures offer the opportunity for unique intracranial interventions such as the ability to record and stimulate intracranially within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and available resources, and frequently the resulting datasets need to be aggregated across sites to achieve sufficient statistical power. To overcome these fundamental barriers and to investigate high-impact questions in human neuroscience, this Notice of Funding Opportunity (NOFO) seeks applications to assemble diverse, integrated, multi-disciplinary teams that cross boundaries of interdisciplinary collaboration. The research should be proposed as exploratory research and planning activities to establish feasibility, proof-of-principle and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain, as described in the companion NOFO (RFA-NS-22-041). Projects should maximize opportunities to conduct innovative in vivo neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and by quantitative, mechanistic models where appropriate.

Recipients will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.

Letter of Intent deadline: August 22, 2023

Application deadline: 9/22/2023

Link to Full Announcement: https://grants.nih.gov/grants/guide/rfa-files/RFA-DC-24-001.html

 

DoD Duchenne Muscular Dystrophy Research Program (DMDRP)

  • Idea Development Award (IDA)
  • Translational Research Award (TRA)

Pre-Application (Letter of Intent) deadline: August 2, 2023
Application deadline: August 23, 2022

Link to Full Announcement: https://cdmrp.health.mil/funding/dmdrp

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