The Lipidomics and Metabolomics Core provides consultation for experiment design in study of lipids, polar metabolites and other small molecules, state-of-the-art mass spectrometers, and advanced bioinformatic tools to the entire OUHSC research community and external researchers. Our mass spectrometry-based solutions can be used to study a wide range of biomedical questions from untargeted biomarker discovery, lipid ID in protein-lipd complexes, to targeted quantitation of signaling lipids/polar metabolites and other small molecule toxins.
Services Offered
- Untargeted lipidomics and metabolomics
- Lipid ID in protein-lipd complexes
- Targeted assay for small molecules (lipid mediators, toxins, drug metabolites, PFAS and more)
- Imaging mass spectrometry (DESI and MALDI)
- Bioinformatic analysis
Instrumentations
- Thermo Fisher Scientific Orbitrap IQ-X Tribrid Mass Spectrometer
- Thermo Fisher Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer with ETD
- Thermo Fisher Scientific TSQ Quantis Triple Quadrupole Mass Spectrometer
- SCIEX 7500+ Triple Quadrupole Mass Spectrometer
- Waters Xevo Multi-reflecting time-of-flight (MRT) Mass Spectrometer with Desorption Electrospray Ionization (DESI) XS
- Bruker timsTOF flleX Mass Spectrometer with Matrix Assisted Laser Desorption/Ionization (MALDI)
- Shimadzu MALDI-8030 MALDI-TOF Mass Spectrometer
Software
- MS Dial
- Compound Discoverer
- Skyline
- MetaboAnalyst
- LipidSig