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OUHSC Research News – Monday, October 2, 2023


Published: Friday, September 29, 2023

Notices and Reminders

OUHSC now has a Helicobacter positive mouse breeding facility:
  • Historically mouse breeding only occurred in the Rodent Barrier Facility (RBF), where all colonies must be free from Helicobacter spp.
  • Increasing prevalence, however, of scientifically justified needs to breed Helicobacter spp. positive mouse strains in recent years have risen
  • The VPR office has supported the Department of Comparative Medicine (DCM) so we can start Helicobacter spp. positive breeding in the O’Donoghue Research Building (ORB)
  • All breeding in this facility is 100% facilitated by DCM Colony Management Services
  • The Success of this new breeding program will rely on strict adherence to biosecurity principles, separate facilities, and minimal crossover of personnel between ORB and RBF
  • Complementary Helicobacter spp. negative and positive breeding facilities will now support the ever growing and complex biomedical research landscape on the OUHSC Campus and is consistent with the University Strategic Plan

 

Workshops and Seminars

ORA Training: Introduction to Proposal Preparation & ORA Submission Process

Date: October 31, 2023; 11:00 AM - 12:00 PM 
Location: Zoom 
Description: This session will provide an overview of OUHSC grants policies and procedures, budget development, and grant submission process.

 

ORA Training: Navigating SoonerTrack Part 1

Date: October 17, 2023; 2:00 PM - 3:00 PM
Location: Zoom
Description: This session will cover the basics of SoonerTrack including creating and approving Request Forms, as well as some tips and tricks.
Registration: https://apps.hr.ou.edu/ClassCalendar/Home/Details/28747?campusId=2  

 

ORA Training: Navigating SoonerTrack Part 2

Date: October 18, 2023; 09:00 AM to 10:00 AM
Location: Zoom
Description: This session will be a detailed review of some of the SoonerTrack functions such as search dashboard and discussions.
Registration: https://apps.hr.ou.edu/ClassCalendar/Home/Details/28748?campusId=2 

 

Oklahoma Conference for Statistical Innovation and Application

American Statistical Association Oklahoma Chapter, Department of Biostatistics and Epidemiology at OUHSC, and Oklahoma Shared Clinical and Translational Research co-organized the second Oklahoma Conference for Statistical Innovation and Application in the Era of Data Science which will be held at Hudson College of Public Health in Oct 23rd and Oct 24th. The conference invites 11 well established guest speakers and it also includes student poster competition session. The conference will be in hybrid format including both in-person and zoom options. The theme of the conference is the novel development in biostatistics, statistics, data science and their applications in biomedical research. Registration is needed at the following website for attending the conference: https://obsc.ouhsc.edu/.

 

Web of Life Conference is April 25-26, 2024 held at OU Health Sciences Center campus. For additional information please refer to the attached flyer (WebofLifeConference).

 

OUHSC Funding Opportunities

Presbyterian Health Foundation (PHF) Bridge Grant Program – Request For Applications

  • Cycle III PHF Bridge Grant Program Deadline: November 1, 2023

The primary objective of the PHF Bridge Grant Program is to provide funding to enhance OUHSC faculty competitiveness for extramural funding. OUHSC Principal Investigators are eligible if they meet the following criteria: 1) have submitted an extramural application within the past 18 months that was scored but not funded, 2) are requesting over $750,000 in total direct costs and over $200,000 in total facilities and administration (F&A) costs; and 3) received a review that ranks applications and provides critiques. 

IMPORTANT UPDATE: This program can now provide funding for up to $75,000 for one year. Guidelines and Application Form are attached or can be found at https://research.ouhsc.edu/research-administration/grants/funding-opportunities/phf-funding. If you have any questions, please email  VPR@ouhsc.edu.

 

Oklahoma Nathan Shock Center of Excellence in the Biology of Aging

Call for Applications for 2024 Pilot Project Awards
Application due: October 15, 2023
Link to the full announcement: See attached flyer for more complete information (Nathan Shock Pilot Advertisement).

 

Investigator Initiated Trials Funding Committee (IITFC), Clinical Trials Office-Protocol Support Unit

Description: Grant proposals are being accepted for the 2023 Fall cycle from Stephenson Cancer Center Providers for their investigator-initiated clinical trials (IITs) or translational work for the amount of up to $100,000 for clinical trials, and up to $25,000 for translation research. All applications should be submitted to the Protocol Support Unit at SCC-IIT-Office@ouhsc.edu and should adhere to the Grant template and Submission Checklist provided with this notice. Investigators should request the budget template from the CTO Budget Manager (ClinicalTrialBudgets@ouhsc.edu). 
Deadline: October 9, 2023 at 5 pm CST
Link to the full announcement or a flier: Please refer to the attached flyer for additional funding criteria and details.

 

Office of Technology Commercialization presents the following opportunity for researchers to engage with industry (click here for more information, or email otc@ou.edu or gina-mcmillen@ouhsc.edu).  

  • A multinational pharmaceutical company is seeking novel biology or therapeutic compounds for treatment of Immunology and Inflammation diseases (i.e. asthma, COPD, IBD).  Novel first-in-class or best-in-class preferred; small molecule, large molecule and RNA modalities are of highest interest.  Out of scope: drug repurposing, natural products and herbal medicine.  Submission entails a one-page 200-300 word non-confidential brief.  Deadline 10/30.
  • Daiichi Sankyo is seeking opportunities to collaborate with researchers who have identified protases involved in mediating diseases; of particular interest are diseases that do not currently have protease inhibitor treatment and targeting diseases of the immune system and inflammatory diseases.  Submission entails a one-page 200-300 word non-confidential brief.  Deadline 10/13.
  • Johnson & Johnson Innovation is seeking novel therapeutic approaches of various modality (small molecules, peptides, large molecules and multi-specifics) to inhibit type 2 inflammation in relevant diseases (e.g. atopic dermatitis, asthma, eosinophilic esophagitis).  Oral therapeutics targeting Th2 signaling pathway are of particular interest; other pathways considered if they provide a systemic approach.  Out of scope: inhaled and topical delivery, microbial therapies, drug repurposing and approaches that have no clear differentiation from current approved therapies.  Submission entails a one-page 200-300 word non-confidential brief.  Deadline 10/13.
  • A global fortune 500 company is seeking research and technologies for treatment or prevention of chronic inflammatory skin conditions with extended duration of efficacy.  Of particular interest is validated research ready for further development (i.e. manufacturing or clinical testing).  Any therapeutic approach is of interest as long as minimally invasive and single or minimal number of treatment administrations possible.  Treatment platforms from other disease areas with potential to be applied to pruritis and inflammation are also of interest.  Out of scope:  allergen specific desensitization and new formulations of known small molecules or monoclonal antibodies.  Submission entails a one-page 200-300 word non-confidential brief.  Deadline 10/13.

NOTE: If the project is selected to move forward with a full application, it will need to be routed through SoonerTrack II.

 

NIH Notices 

NOTE: When only one application is allowed per Institution according to the sponsor instructions, a one-page letter of intent summarizing the proposed project should be submitted to the Vice President for Research at least two months prior to the application deadline (unless otherwise noted).  The letters of intent will be reviewed and a single application will be chosen for submission from the University.

 

NIH Funding Opportunities

 

Other Funding Opportunities

Southwest Center for Occupational and Environmental Health (SWCOEH) Pilot Projects Research Training Program

Description: The goal of the Pilot Projects Research Training Program is to enhance Southwest Center for Occupational and Environmental Health (SWCOEH) regional outreach efforts in research training and to foster stronger inter-institutional ties in occupational health research within Public Health Region 6 (PHR 6) (Arkansas, Louisiana, New Mexico, Oklahoma and Texas). The objective of this program is to provide a support mechanism for pilot research projects initiated by:
  • Research Trainee Awards: Graduate students or postdoctoral fellows in an occupational health and safety-related discipline.
  • Junior Investigator Awards: New investigators with research interests in the general area of occupational health and safety. Junior investigators are defined as faculty who have not served as PI on any Public Health Service (PHS)-supported research grants other than a R03, R15, R21, K01, K08, or K12.
  • New Researcher Awards: Researcher or Faculty in areas other than occupational health research who wish to apply their expertise to an occupational safety and health issue.
Letter of Intent Deadline: September 29, 2023
Application Deadline: October 29, 2023

 

Chan Zuckerberg Initiative (CZI) Request for Applications: Single-Cell Biology Data Insights Cycle 3 RFA

Description: The Chan Zuckerberg Initiative (CZI) invites applications for Cycle 3 of the Single-Cell Biology Data Insights RFA. CZI seeks to support projects that will advance the fields of single-cell biology and data science. Projects may include dedicated efforts to democratize access and usability of existing single-cell datasets, demonstrate utility by leveraging existing single-cell datasets to address impactful and challenging biological questions, and develop methods that enable greater biological insight and other major challenges brought forward.
This request for applications is the last of three currently planned cycles, with successful projects receiving 18 months of funding support. Awards are a maximum of $400,000 in total costs for Expanded Projects, and $200,000 in total costs for Focused Projects.
Application Deadline: December 5, 2023

 

Conquer Cancer Grants & Awards

The Conquer Cancer Grants & Awards Program offers a comprehensive portfolio of funding opportunities for every career stage. Conquer Cancer supports the brightest minds in cancer research in every aspect of oncology, from prevention and diagnosis to treatment and survivorship.
  • Young Investigator Award (YIA)The YIA provides research funding to promising physicians to support the transition from final years of training to faculty appointment and to encourage and promote quality research in clinical oncology. Applications in all areas of cancer research are accepted from U.S. and international applicants, and there is dedicated funding for disease sites and topics. Applications are due September 21, 2023, by 11:59 PM (ET).
Applications are due January 31, 2024, by 11:59 PM (ET):
  • YIA in Drug Development
  • YIA in Geriatric Oncology
  • YIA in Cancer Supportive Care
  • YIA in Primary Brain Tumors
Applications are due March 14, 2024, by 11:59 PM (ET):
  • YIA in Mantle Cell Lymphoma
  • YIA in Chronic Lymphocytic Leukemia
  • YIA for Diversity and Inclusion in Breast Cancer Research
The CDA provides research funding to clinical investigators, who have received their initial faculty appointment, as they work to establish an independent clinical cancer research program. This is a mentored award and the research project is conducted under the guidance of a scientific mentor. Applications are due October 19, 2023, by 11:59 PM (ET).
CDA for Diversity and Inclusion in Breast Cancer Research–Applications are due March 14, 2024, by 11:59 PM (ET).
The ACRA is designed with the primary goal of increasing diversity in the oncology workforce and cancer research. Awards will be given to mid-career investigators who are members of racial and/or ethnic groups traditionally excluded in academic medicine and biomedical research, and who wish to conduct original breast cancer research not currently funded. Letters of Intent are due November 16, 2023, by 11:59 PM (ET).
The WWCC Mentorship Award recognizes extraordinary women leaders in oncology and role models who have excelled as a mentor and have demonstrated outstanding commitment to the professional development of women colleagues as clinicians, educators, and researchers in oncology. Nominations are due December 15, 2023, by 11:59 PM (ET).
The purpose of this award is to facilitate collaborations involving a diverse team of investigators, directed toward developing treatment options for childhood medulloblastoma. This is a $100,000 grant from Carson Leslie Foundation and #cureMEdullo, with Conquer Cancer serving as the lead organization for grant administration. Letters of Intent are due September 29, 2023, by 11:59 PM (ET).

 

The Bill & Melinda Gates Foundation (BMGF) and Wellcome: Strengthening Health and Disease Modeling for Public Health Decision Making in Africa

Description: The Bill & Melinda Gates Foundation and Wellcome have launched a new request for proposals, "Strengthening Health and Disease Modelling for Public Health Decision Making in Africa."
Local modeling expertise is critical to effective public health decision making, and the community of modelers across Africa is growing. With this in mind, the Gates Foundation and Wellcome recently co-hosted a workshop with over 100 African modelers and other stakeholders to discuss how to strengthen the public health modeling ecosystem on the continent. This request for proposals was shaped by the themes of those discussions. We seek to support modelling projects that answer important public health questions, that are actionable enough to result in policies that improve people’s health, and that strengthen the African modelling ecosystem by developing new approaches and tools or connecting modelers and policymakers across countries and institutions.
Application Deadline: October 23, 2023

 

Susan G. Komen ASPIRE: A Supplement to Promote Inclusion for Research Excellence 

Description: This new Susan G. Komen grant is intended to enhance the diversity of the breast cancer research workforce by providing established breast cancer scientists with supplemental funding to support research trainees from communities historically minoritized and marginalized in research. By supporting these promising trainees early in their research careers, Komen seeks to ensure that a diverse group of highly trained scientists who reflect the communities we serve will emerge as the next generation of leaders in breast cancer research and end breast cancer forever.  
Eligibility: Lead mentor must have a currently funded breast cancer research project that has undergone a rigorous peer review (see request for application for link of organizations that fall under this category). Trainees supported with this supplement are from groups shown to be historically minoritized and marginalized in biomedical research from National Science Foundation data. This includes individuals who identify as Black or African American, Latino or Hispanic, American Indian or Alaska Native, Native Hawaiian and other Pacific Islanders; individuals with disabilities; and individuals from disadvantaged backgrounds according to the criteria used by the NIH (https://diversity.nih.gov/about-us/population-underrepresented). Eligibility for disadvantaged background will be measured using the same characteristics as the NIH, i.e., at least two of the criteria must be met to be included. 
Award amount: up to $100,000 per year to cover a trainee’s salary for one year or two years. 
Full Application Due: November 1, 2023, by 1 p.m., Eastern Standard Time 
Additional Information: https://bit.ly/3xmfvcn 

  

Documents to download