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Research News – Monday, March 4, 2024


Published: Monday, March 4, 2024

Notices and Reminders
 
New Marketing and Communication Process for Research Activities
OU Health Sciences now has a dedicated marketing and communications team, including a writer who publicizes research activities across campus. If you have research news, please email April Wilkerson at April-J-Wilkerson@ouhsc.edu or call extension 33182. Newly awarded grants, recent publications, national awards, public service and community outreach activities are among the potentially newsworthy items. If possible, please notify April as early as possible about upcoming publications.
 
OUHSC F&A Rate Agreement:  The University has recently received the F&A (IDC) rate for our proposal submitted in 2021.  The new rates are retroactive to July 1, 2023.  Grants and Contracts accounting has identified the federal and federal flow through awards that have been newly awarded since July 1, 2023 and will be updating the F&A rate for those projects.  This will create a credit that we will return to our sponsors.  A memo will be issued to our federal flow through sponsors with the February invoice to explain the F&A credit.  Projects funded in previous years will continue to use the rate that was in place at the time of awarding per federal regulations.  Please feel free to contact Michelle Bremenkamp if you have any further questions or concerns. 
 
Center for Indigenous Resilience, Culture, and Maternal Health Equity (CIRCLE)
CIRCLE is a new NIH-funded Center of Excellence focused on Indigenous maternal health research in Oklahoma and the Southern Plains. OUHSC researchers have partnered with the Southern Plains Tribal Health Board and faculty from partnering institutions to identify root causes and intervene to reduce the disproportionately high rates of Indigenous maternal morbidity and mortality. CIRCLE goals include training and development of early career researchers and practitioners and working closely with our community partners in research and outreach.  To connect with CIRCLE as an affiliate, please complete the CIRCLE interest webform.
Save the Date: CIRCLE is pleased to announce our second CIRCLE Seminar Series presentation by Dr. Emily Jones, “Building Capacity to Advance Indigenous Maternal Health Equity in the Southern Plains,” to be held in the Bird Auditorium on March 7th from 1:00-2:00pm. 
Join via Zoom Meeting ID: 943 7477 8472; Passcode: 83174790
 
OUHSC Editing and Grant Writing Support: The VPR office will be hiring an in house editor that has vast experience in editing and writing manuscripts and grant proposals, but will not be on board until late spring. In the interim, there is also a service of freelancers that can help in this regard.  The editing, writing services provided by Eloquenti has extended to us at the University of Oklahoma Health Sciences an opportunity to receive scientific editing and grant writing support at a discounted rate. Eloquenti is a network of professional editors and grant writers specializing in medicine and natural sciences, trusted by numerous universities, research institutes, and peer-reviewed journals. To benefit from this offer, simply use the code OUHSC23 when booking any project on Eloquenti, which is a marketplace of freelancers and scientific experts for proofreading services, copy editing services, technical writing, grant writing, and book writing. Please use the vendor id 9100091739 and each department will be responsible for payment by entering a requisition to receive a purchase order through purchasing.
 
 
Workshops and Seminars
 
2024 Oklahoma Geroscience Symposium
April 11, 2024 | Nicholson Conference Center, OKC
The Oklahoma Nathan Shock Center of Excellence is proud to host the 2024 OKLAHOMA GEROSCIENCE SYMPOSIUM: Mitochondria in aging and age-associated disease. The symposium will feature a Keynote Lecture by Doug Wallace, PhD and other world-renowned speakers in aging and Geroscience research, a Funders’ Roundtable, Poster Session, and Trainee/Faculty Mixer.
 
2024 Web of Life Conference
Date: 4/25/2024 - 4/26/2024
Location: Nicholson Auditorium, 1000 NE 13th St, Oklahoma City, OK 73104
Description: Major diseases such as cancer, cardiovascular disorders, diabetes, obesity, aging, and neurodegeneration are often studied and treated in isolation. Yet, each of them may be related, causally or otherwise, to one another. Therefore, facilitating crosstalk among these is expected to foster multidisciplinary collaboration and drive innovative and effective solutions.
The two-day Web of Life Conference will be hosted for the first time by the University of Oklahoma Health Sciences Center in April 2024. To realize the full potential of team science, we are bringing stalwarts from disparate yet connected fields such as cancer, diabetes, ageing bioengineering, and neurodegeneration to unite them under the common theme - “Web of Life: Connecting the Dots.” This collaboration will significantly impact and improve the way we engage communities, treat patients, foster collaboration, and facilitate groundbreaking discoveries.
 
 
OUHSC Funding Opportunities
 
Investigator Initiated Trials Funding Committee (IITFC), Clinical Trials Office-Protocol Support Unit
Description: Grant proposals are being accepted for the 2024 Spring cycle from Stephenson Cancer Center Providers for their investigator-initiated clinical trials (IITs) or translational work for the amount of up to $100,000 for clinical trials, and up to $25,000 for translation research. All applications should be submitted to the Protocol Support Unit at SCC-IIT-Office@ouhsc.edu and should adhere to the Grant template and Submission Checklist provided with this notice. Investigators should request the budget template from the CTO Budget Manager (ClinicalTrialBudgets@ouhsc.edu) and seek Statistician support at https://redcap.ouhsc.edu/redcap/surveys/?s=HWX4XPMELM.  Please refer to the attached flyer for additional funding criteria and details.
Deadline: April 15th, 2024 at 5 pm CST
 
 
Presbyterian Health Foundation (PHF) Technology Advancement Grant (TAG) Program – Request For Applications
  • Cycle I PHF TAG Grant Program Deadline: ROLLING APPLICATIONS
The TAG program replaces the Equipment grant program. The primary objective of the PHF TAG program is to provide partial funding for critically needed research equipment that could be transformative for the research mission at OUHSC. This program is fully aligned with Pillar 1 of the Strategic Plan. The TAG program will proactively and with the help of a committee address campus-wide needs and fill critical gaps, with the goals to grow the research enterprise, expand innovative technology and research infrastructure, and promote addition of new cutting-edge technology on campus. Funding priority will be given to research equipment that will permit OUHSC investigators to be more competitive for external funding and provides support to multiple users. Funds may be used for equipment to be purchased as part of a recruitment package for new faculty or for equipment to support the research of current faculty. If the funds will be used for a new recruit, the recruit must have signed the offer letter with a specific start date or specific start date time frame. Equipment and/or technology funded by PHF is expected to be made available to all researchers at OUHSC, whenever possible.
All OUHSC Assistant, Associate, or Full Professors are eligible to apply. Applicants are required to match requested funds. The maximum allowable budget for this program is $500,000 (PHF funding: $250,000; Applicant funding: $250,000). The minimum allowable budget for this program is $60,000 (PHF funding: $30,000; Applicant funding:  $30,000). Only one application will be accepted per investigator per year.
 
Presbyterian Health Foundation (PHF) Seed Grant Program – Request For Applications
  • Cycle I PHF Seed Grant Program Deadline: March 22, 2024
The primary objective of the PHF Seed Grant program is to provide a one-year grant for new OUHSC investigators to initiate research programs. Secondary objectives are to provide established OUHSC faculty with the opportunity to initiate new unfunded projects and to provide unfunded OUHSC faculty funds to initiate a research program. Applications from new investigators (within 5 years of first full academic appointment and never having received independent federal funds) are given special consideration during peer review and at the time of funding consideration. Principal Investigators with Temporary Faculty appointments (faculty with academic titles such as instructor, lecturer, or titles modified by prefixes such as visiting, adjunct, clinical, or temporary research appointments with suffix “of Research”) must obtain approval from the Vice President for Research before submitting an application for this program. Approval will require a letter from their Department Chairperson indicating a departmental commitment of salary, research space, and time for development of an independent career at OUHSC.  Requests should be sent to ORA4PHF@ouhsc.edu PHF Seed Grant recipients may not hold a PHF Bridge Grant or a PHF Clinician Scientist Development Grant during the duration of this award.
IMPORTANT UPDATE: This PHF Seed Grant program can now provide funding for up to $75,000 for one year.
 
Presbyterian Health Foundation (PHF) Bridge Grant Program – Request For Applications
  • Cycle I PHF Bridge Grant Program Deadline: April 1, 2024
The primary objective of the PHF Bridge Grant Program is to provide funding to enhance OUHSC faculty competitiveness for extramural funding. OUHSC Principal Investigators are eligible if they meet the following criteria: 1) have submitted an extramural application within the past 18 months that was scored but not funded, 2) are requesting over $750,000 in total direct costs and over $200,000 in total facilities and administration (F&A) costs; and 3) received a review that ranks applications and provides critiques. 
 
Presbyterian Health Foundation (PHF) Clinical Translational Grant Award (CTGA) Program – Request For Applications
  • Cycle I PHF CTGA Program Deadline: March 29, 2024
The CTGA program will replace the Team Science program. The primary objective of this PHF CTGA mechanism is to grow collaborations and expand innovative healthcare research activities and promote collaboration among faculty to help OUHSC achieve the goals outlined in Pillar 1 of the Strategic Plan. The investigators must consist of one basic science researcher and one clinician researcher who can develop a broadly based, multidisciplinary research program focused on a specific disease entity, biomedical problem area, or clinically relevant problem. The proposal must focus on the collaborative relationship, such that the scientific objectives could not be achieved without the efforts of a basic science researcher, a clinician researcher, and their respective expertise and/or disciplines. It is expected that both members of the investigator team will devote an equivalent amount of effort to the project (60/40 or 50/50 distribution of effort).
The funding for this program can be for up to two years. The second year of funding, if funds are available, will be based on successful achievement of identified milestones as noted by the researchers in the Year 1 application and quality of specified milestones to be met during the next year of funding, as documented in the completed Year Two application form.
This funding opportunity is intended to:
  • Promote collaborative scientific interactions among investigators
  • Support translation of novel basic/pre-clinical observations or the translation, dissemination, and implementation of clinical observations to community settings
  • Foster engagement of interdisciplinary teams
  •    Support collaborative interactions among clinical and fundamental research investigators leading to co-authored papers and grant applications.
PHF CTGA awardees may hold PHF Symposium grants, Technology Advancement Grants (TAG), or Bridge grants throughout the duration of this award, but may not serve as the Contact PI/Team Leader on more than one PHF Clinical Translational Grant. A single investigator may only be awarded one CTGA award at a time, whether as contact PI or collaborating PI.
 
Presbyterian Health Foundation (PHF) New Investigator Seed Grant Program –Year 2 ONLY-  Request For Applications
  • Cycle I PHF New Investigator Seed Grant Year 2 Program Deadline: March 8, 2024
The primary objective of the PHF New Investigator Seed Grant Program is to provide a two-year grant for OUHSC New Investigators to initiate research programs and obtain extramural funding. Applicants must fit the following definition of a New Investigator: An investigator who has not previously received substantial, independent funding from NIH (e.g. R01-type funding) or a comparable funding agency. Multi-PI applications are not allowed. Applicants must have received a Year 1 New Investigator Seed Grant and  be nominated by their professional college in order to apply for this award. The professional college nominating the faculty member must agree to assign a mentor for this project and must commit to providing the mentor with $2,500/year for mentoring activities; the mentor does not need to be an OUHSC faculty member. Each college may set up their own nomination process for this award; however, completion and submission of the PHF Year 2 New Investigator Seed Grant Critique Form is required with this application.  
The Principal Investigator must be an OUHSC primary faculty member. Principal Investigators with Temporary Faculty appointments (faculty with academic titles such as instructor, lecturer, or titles modified by prefixes such as visiting, adjunct, clinical, or temporary research appointments with suffix “of Research”) must obtain approval from the Vice President for Research before submitting an application for this program. Approval will require a letter from their Department Chairperson indicating a departmental commitment of salary, research space, and time for development of an independent career at OUHSC. Requests should be sent to ORA4PHF@ouhsc.edu
IMPORTANT CHANGE: There is no first-year funding opportunity in 2024; after this second-year funding opportunity, this program will be discontinued.
PHF New Investigator Seed Grant recipients may not hold a PHF Bridge Grant, a PHF Clinician Scientist Development Grant, a PHF Team Science Grant, a Research Support Grant, or a PHF Seed Grant for the duration of this award.
 
Presbyterian Health Foundation (PHF) Clinician Scientist Development Grant Program – Request For Applications
  • Cycle I PHF Clinician Scientist Development Grant Program Deadline: March 8, 2024
The primary objective of the PHF Clinician Scientist Development Grant Program is to provide funding to a new or early stage clinician scientist faculty member. This award is designed to support the applicant’s clinical and/or translational research project and to assist him or her with advancing this research project to a level that will be competitive for funding through a federal career development award mechanism. This program can provide funding for up to two years. The second year of funding, will be based on successful achievement of identified milestones, completion of an application for Year Two funds, and whether funds are available.
The Principal Investigator must be an OUHSC primary faculty member with appointment at OUHSC as an Assistant Professor. New or early stage clinical scientist faculty members with Temporary Faculty appointments (faculty with academic titles such as instructor, lecturer, or titles modified by prefixes such as visiting, adjunct, clinical, or temporary research appointments with suffix “of Research”) must obtain approval from the Vice President for Research before submitting an application for this program. Approval will require a letter from their Department Chairperson indicating a departmental commitment of salary, research space, and time for development of an independent career at OUHSC.  Requests should be sent to ORA4PHF@ouhsc.edu). Applicants must not have had a prior NIH career development award or an independent NIH R01 award; must have an independent clinical and/or translational research project; must have an identified senior, experienced research mentor; and may not have another PHF grant during the duration of this award.  
 
College of Medicine Research Fund
Proposals are being accepted from full-time faculty of the College of Medicine for grants to be awarded from the College of Medicine Alumni Association with proceeds generated from the Evening of Excellence dinner fund.  COMAA awards are intended to be an important resource for funding basic and clinical research projects of new and early-stage investigators in the College of Medicine. The guidelines are attached. Successful applicants will be designated “College of Medicine Alumni Research Scholars.”  Applications will be reviewed by a scientific panel whose composition will be based on the types of applications received.  Awards generally fall within the $20,000 to $50,000 range ($50,000 maximum request). 
Applications should be sent electronically to COMAA-Research@ouhsc.edu by 5 pm on April 12, 2024. 
All applications must be routed through the Office of Research Administration and include the NIH face page (https://grants.nih.gov/grants/funding/phs398/fp1.pdf) signed by the appropriate ORA institutional official.
Office of Technology Commercialization presents the following opportunity for Office of Technology Commercialization presents the following opportunity for researchers to engage with industry (click here for more information, or email otc@ou.edu or gina-mcmillen@ouhsc.edu).  
  • Cumulus Oncology is interested in the identification of specific molecular targets and biomarkers associated with ferroptosis, which allow for the development of targeted therapies.  Platforms to identify ferroptosis targets and opportunities for combination therapy are also within scope.  All cancers and modalities (including small molecule, biologics and mRNA) are of interest.  Out of scope:  drug-repurposing, gene therapy and cell therapies.   Submission entails a one-page 200-300 word non-confidential brief.  Deadline March 20th.
 
 
 
NOTE: When only one application is allowed per Institution according to the sponsor instructions, a one-page letter of intent summarizing the proposed project should be submitted to the Vice President for Research at least two months prior to the application deadline (unless otherwise noted).  The letters of intent will be reviewed and a single application will be chosen for submission from the University.
 
NIH Funding Opportunities
 
 
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional) (PAR-24-119)
Application Deadline:  June 18, 2024 and October 17, 2024
 
 
 
Addressing Health Inequities in Clinical Diagnostics (R41/R42 Clinical Trials Not Allowed)
(PAR-24-157)
Application Deadline:  September 5, 2024 and January 5, 2025
 
Addressing Health Inequities in Clinical Diagnostics (R43/R44 Clinical Trials Not Allowed)
(PAR-24-158)
Application Deadline:  September 5, 2024 and January 5, 2025
 
 
Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional) (PAS-24-163)
Application Deadline:  May 7, 2024 and September 7, 2024
 
 
 
 
 
 

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