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Research News – Monday, September 30, 2024


Published: Monday, September 30, 2024

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ANNOUNCEMENTS

The Office of Research Administration Grants Team is currently understaffed by two positions, and we are expecting a high volume of applications for the October 7th NIH deadline. Please advise your PIs that processing times may take longer than usual so the sooner they can complete their application, the sooner it can be reviewed and submitted. If you have a list of upcoming application submissions, it would be helpful if you send it to your Sponsored Programs Administrator so we can review workloads of each individual and the team as a whole.
Waiver requests under ORA’s 3-day review deadline policy will be heavily scrutinized and approval will depend on the volume of timely received applications. ORA’s internal deadline for the October 7th deadline is October 2nd at 5:00 PM. Please note that per our policy, all documents must be in their final form, including science documents, to meet our 3-day review requirement. ORA will move forward with submission once we have completed our review to avoid a backlog on the day of the deadline.   
Please read the attached document completely for complete details.
 
Health Research Associates (HRA) Services (Dr. Sally Atherton) Update
After September 30, 2024, HRA Services (Dr. Sally Atherton) will no longer be funded through the VPR office. OUHSC investigators retain access to and may use her services at their department’s expense. After September 30, 2024, HRA Services will invoice departments directly. The department will be responsible for payment. 
  
New OUHSC Policy Effective September 9, 2024: Research-Related Resource Requests
There is a new policy in effect for all research-related requests (e.g., equipment, startup funds, recruitment, retention, etc.).  The full policy is provided as an attachment and below is a summary.  Please circulate as needed to your business manager and faculty.  Your observance of this policy is greatly appreciated.
  1. The faculty member requests research support from their department chair.
  2. The department chair will review and determine the level of support to be provided by the department.
  3. If the chair supports seeking some resources from a Center, if utilized, the chair will coordinate the level of support with the Center Director and include the commitment in the request.
  4. The chair will forward the request including the department and Center commitments to the college dean.
  5. The college dean will review the department and Center commitments and determine the level of additional college support that may be provided.  If commitments from the department, Center and college do not meet the research support needed, then the dean will forward the summary of commitments to the Vice President for Research to request the remaining support.
  6. The Vice President for Research will review all commitments and communicate the request to the Senior Vice President and Provost to determine if additional support will be funded by the university and to what extent.
  7. The Vice President for Research will communicate funding decisions to the faculty member, chair, Center director (if necessary), and dean.
  8. If support is approved, the faculty member will provide draft letters of support to the Office of the Vice President for Research and the Office of the Senior Vice President and Provost as applicable.
This policy has been generated and edited by the Office of the Vice President for Research, various chairs of the basic science departments, various deans of colleges, and members of the Provost’s office, including the Senior Vice President and Provost, Dr. Raskob. Please direct any questions to the Office of the Vice President for Research at vpr@ouhsc.edu
 

WORKSHOPS AND SEMINARS

Department of Psychiatry & Behavioral Sciences Second Annual Research Symposium 
 Registration is now open for the Department of Psychiatry & Behavioral Sciences 2024 Research Symposium on Friday, November 22, 2024, at the Samis Education Center from 9:00 AM to 2:00 PM
We are excited to announce that Paul J. Frick, Ph.D., Professor in the Department of Psychology at Louisiana State University, will be the plenary speaker. His research presentation is titled “Developmental Pathways to Conduct Disorder: Implications of the DSM-5 Specifier ‘With Limited Prosocial Emotions.’” 
We invite all members of the OUHSC, College of Medicine to join us for this free event. Further details regarding the symposia speakers and the full agenda will be shared next month. If you're interested in attending, please register using the following link. 
For any inquiries or questions about this event, please contact psychiatry-research@ou.edu.
 
Organized by the OK-INBRE and the OUHSC IRCF, Qiagen will present a one-day training session by Tim Hou, Field Application Specialist, on the Ingenuity Pathway Analysis software. This training session will be held on October 4, beginning at 9AM in BRC109 (see attached flyer). Basic functions of the IPA analysis pipeline will be presented, to give you insight into how to use this important software for your research needs. After lunch (which will be provided), additional sessions on data mining of the IPA database and an ‘Office Hour’ for individual consultation will be available. If you wish to attend, please register (for free) at the URL or use the QR code on the attached flyer. Hope to see you there!  ATTACHMENT
 
CALLING ALL STUDENTS: The Oklahoma Conference for Statistics, Biostatistics, and Data Science invites students to submit a poster for presentation during the conference on Tuesday, October 15. Two winners will receive a $200 award. Submit your posters to sixia-chen@ouhsc.edu by October 7, 2024. 
 
The 2024 Oklahoma Conference for statistical innovation and application in the era of data science is coming to the OU Hudson College of Public Health on Monday, October 14 and Tuesday, October 15. Registration is now open and includes lunch, snacks, beverages, live presentations, interaction and social networking with speakers, and a copy of the recorded presentations each day! Virtual and in-person session options are available. Special rates for students!
Visit https://obsc.ouhsc.edu/ to see the agenda, details and accommodations.  Register here by October 9, 2024

 

FUNDING OPPORTUNITIES

Geroscience T32 Positions Available for Pre- and Post-doctoral Fellows
The Geroscience T32 NIH training program currently supports 3 post-doctoral fellows and 5 graduate students with research interests in the field of geroscience. The goal of the program is to offer training and mentorship to young investigators to significantly advance their careers in fields related to geroscience and aging research. The program focuses on the interaction between biological aging and disease (aging as a risk factor for disease). These areas include, but are not limited to, mechanisms of brain aging (including Alzheimer’s Disease), neurodegeneration, cellular senescence, neuronal glycolysis, caloric restriction, oxidative stress, molecular biology of aging, mitochondria dysfunction, genomics, metabolomics, sarcopenia, and gero-oncology.  See attached document for additional information.
Send applications to (william-sonntag@ouhsc.edu & melissa-k-day@ouhsc.edu) as a single pdf file with your last and first names.
Applications are due Friday, October 18th at 5:00pm.
 
OSCTR TPIR Trainee Program
Seeking applicants for the eleventh year of the research training program Translating Practice into Research (TPIR). TPIR is a program for healthcare professionals, clinical investigators, basic scientists, and community health professionals and it is funded by the NIH Oklahoma Shared Clinical and Translational Resources grant. The goal of the TPIR trainee program is to produce a group of clinicians and scientists who have the ability to translate their clinical observations and ideas for improving practice into practical and feasible research projects. The application is due October 7, 2024.  
 
Oklahoma Nathan Shock Center: Pilot Award Opportunity
Description: The Oklahoma Nathan Shock Center is soliciting applications to support the research of early-stage investigators, and senior investigators initiating new research programs in aging/geroscience, that can serve as the base for the development of new applications for NIA funding. The projects should utilize services provided by the Oklahoma Nathan Shock Center Cores as described on the NSC website (oklahomanathanshockcenteronaging.org). The awards range from $5,000 to $20,000 depending on the specific needs of the applicant. Applications from outside the University of Oklahoma Health Sciences, the Oklahoma Medical Research Foundation, and the Oklahoma City VA Health Care system, as well as collaborative projects with other Nathan Shock Centers are strongly encouraged.
Deadline for Submission: October 18, 2024
Link to the Full Announcement: Please see attached (Oklahoma Nathan Shock Pilot 2024)
 
Presbyterian Health Foundation (PHF) Clinician Scientist Development Grant Program – Request for Applications
Cycle I PHF Clinician Scientist Development Grant Program Deadline: October 2, 2024
The primary objective of the PHF Clinician Scientist Development Grant Program is to provide funding to a new or early-stage clinician scientist faculty member. This award is designed to support the applicant’s clinical and/or translational research project and to assist him or her with advancing this research project to a level that will be competitive for funding through a federal career development award mechanism. This program can provide funding for up to two years. The second year of funding will be based on successful achievement of identified milestones, completion of an application for Year Two funds, and whether funds are available.
The Principal Investigator must be an OUHSC primary faculty member with appointment at OUHSC as an Assistant Professor. New or early-stage clinical scientist faculty members with Temporary Faculty appointments (faculty with academic titles such as instructor, lecturer, or titles modified by prefixes such as visiting, adjunct, clinical, or temporary research appointments with suffix “of Research”) must obtain approval from the Vice President for Research before submitting an application for this program. Approval will require a letter from their Department Chairperson indicating a departmental commitment of salary, research space, and time for development of an independent career at OUHSC.  Requests should be sent to ORA4PHF@ouhsc.edu). Applicants must not have had a prior NIH career development award or an independent NIH R01 award; must have an independent clinical and/or translational research project; must have an identified senior, experienced research mentor; and may not have another PHF grant during the duration of this award.  
 
2025 OK-INBRE Research Project Investigator Awards – Request for Proposals
Deadline: October 31, 2024
The Oklahoma IDeA Network for Biomedical Research Excellence (OK-INBRE) is soliciting applications for its Research Project Investigator (RPI) award program.  The purpose of the RPI program is to foster and develop biomedical research programs designed to generate preliminary data that enhances the competitiveness of the investigator for future extramural funding.   Full-time, tenure track faculty members (or equivalent) at the University of Oklahoma Health Sciences or the Oklahoma Medical Research Foundation who qualify as an Early-Stage Investigator as defined by the NIH are eligible to apply.  Awarded projects will receive up to $100,000 in direct costs per year plus applicable F&A costs for up of two years.  The forms, instructions, and submission information can be found on the OK-INBRE website.  Questions regarding this OK-INBRE funding opportunity can be directed to okinbre@ouhsc.edu or Dr. Mark Lang at mark-lang@ouhsc.edu.
 
Presbyterian Health Foundation (PHF) Technology Advancement Grant (TAG) Program – Request For Applications
Cycles I-III PHF TAG Grant Program Deadline: ROLLING APPLICATIONS
The TAG program replaces the Equipment grant program. The primary objective of the PHF TAG program is to provide partial funding for critically needed research equipment that could be transformative for the research mission at OUHSC. This program is fully aligned with Pillar 1 of the Strategic Plan. The TAG program will proactively and with the help of a committee address campus-wide needs and fill critical gaps, with the goals to grow the research enterprise, expand innovative technology and research infrastructure, and promote addition of new cutting-edge technology on campus. Funding priority will be given to research equipment that will permit OUHSC investigators to be more competitive for external funding and provides support to multiple users. Funds may be used for equipment to be purchased as part of a recruitment package for new faculty or for equipment to support the research of current faculty. If the funds will be used for a new recruit, the recruit must have signed the offer letter with a specific start date or specific start date time frame. Equipment and/or technology funded by PHF is expected to be made available to all researchers at OUHSC, whenever possible. All OUHSC Assistant, Associate, or Full Professors are eligible to apply. Applicants are required to match requested funds. The maximum allowable budget for this program is $500,000 (PHF funding: $250,000; Applicant funding: $250,000). The minimum allowable budget for this program is $60,000 (PHF funding: $30,000; Applicant funding:  $30,000). Only one application will be accepted per investigator per year.  ATTACHMENT
 
New Clinical Study Opportunities
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Please note this is NOT a solicitation for study subjects
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Several Pharmaceutical companies are looking for Principal Investigators to participate in the following clinical studies:
  • Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors
    • This study is a phase IV, pragmatic single-arm prospective, open label study in pediatric (6 years or older) and adult study participants with rare BRAF V600E mutation-positive unresectable or metastatic solid tumors for whom a decision has already been made to be treated with dabrafenib and trametinib, irrespective of the trial participation
  • Pfizer - Request for Proposals (RFP) Education for Patients and Caregivers Living With Bladder Cancer from Non-Muscle Invasive Bladder Cancer (NMIBC) to Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC)
  • Pfizer - Request for Proposals (RFP) PARP-Inhibitor Combination Treatments: Safety and Efficacy in a rapidly changing metastatic Castration Resistant Prostate Cancer (mCRPC) landscape
  • Pfizer - Request for Proposals (RFP) Clinical Data Updates and Treatment Management Strategies in First-line ALK-positive Metastatic Non-Small Cell Lung Cancer (NSCLC)
  • Pfizer Request for Proposals (RFP) Education in the Era of Emerging Hemophilia Therapy
  • Pfizer - Request for Proposals (RFP) Clinical Data Updates and Treatment Management Strategies in First-line ALK-positive Metastatic Non-Small Cell Lung Cancer (NSCLC)
  • Pfizer - Request for Proposals (RFP) ncrease Awareness & Understanding of Emerging Hemophilia Treatment Options
  • Pfizer Independent Medical Education Request for Proposals USP <797> Pharmaceutical Compounding-Sterile Preparations: Ensuring Compliance Now and For the Future
Please contact Scott Davis at scott-davis@ouhsc.edu if you would like to receive more information on any of these studies. The resulting confidentiality and/or clinical study agreement will need to be routed to the Office of Research Administration.

NIH NOTICES

 
 
NOTE: When only one application is allowed per Institution according to the sponsor instructions, please send a copy of the guidelines to HSCORA@ouhsc.edu as soon as the PI or department is aware of limited eligibility. ORA will review and provide further instructions regarding next steps in the process.

NIH FUNDING OPPORTUNITIES

 
 
 
NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed) (PAR-24-301)
Application Deadline:  January 25, 2025 
 
 
 
 
Precision Medicine for Type 1 Diabetic Nephropathy (U01 Clinical Trial Not Allowed) (RFA-DK-25-022)
Application Deadline:  December 10, 2024
 
 
 
 
 
 
 
 
 
NIH Loan Repayment is now accepting LRP applications until Thursday, November 21, 2024.
The LRPs offer unique opportunities with significant benefits to early-stage researchers.  The LRP can provide up to $100,000 towards federal and private student loans in exchange for a two-year commitment to conducting qualified research.
There will be an LRP technical assistance webinar on October 7th at 3 PM EST (Registration link) to support applicants.
For additional information please see the attached document or visit the LRP website.  

OTHER FUNDING OPPORTUNITIES

Komen’s newest RFA for our ASPIRE program can be found at: https://www.komen.org/breast-cancer-research/grants/opportunities/
Briefly, this grant mechanism is intended to enhance the diversity of the breast cancer research workforce by providing established breast cancer scientists with supplemental funding to support research trainees from communities historically minoritized and marginalized in research. A breast cancer research workforce that represents the breast cancer community is one way to work towards health equity and better outcomes for all. For these purposes, Komen is using the NIH criteria for racial/ethnic minorities, people with disabilities and people from disadvantaged backgrounds as our qualifiers. Happily, breast cancer has gender parity in researchers, but that means for these purposes, identifying as a woman is not qualifying here.  
Additionally, we are not limiting this opportunity, your institution is welcome to submit as many applications as they have eligible PIs and trainees. Notably, we also do not have an LOI step for these applications and instead have applicants submit applications directly in one step. The deadline for these is November 4, 2024.  
Please respond to this email or email MissionGrantsAdmin@komen.org if you have any questions!   

 

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